Highest fours in career:
| PLAYER | COUNTRY | MATCHES | RUNS | HIGHEST | 6's | 4's |
| SR Tendulkar | India | 458 | 18111 | 200 | 193 | 1981 |
| ST Jayasuriya | Sri Lanka | 450 | 13428 | 189 | 270 | 1500 |
| RT Ponting | Australia | 361 | 13406 | 164 | 161 | 1195 |
| AC Gilchrist | Australia | 287 | 9619 | 172 | 149 | 1162 |
| SC Ganguly | India | 312 | 11363 | 183 | 190 | 1122 |
| V Sehwag | India | 242 | 7760 | 175 | 128 | 1068 |
| BC Lara | West Indies | 298 | 10405 | 169 | 133 | 1035 |
| Inzamam-ul-Haq | Pakistan | 378 | 11739 | 137 | 144 | 971 |
| CH Gayle | West Indies | 226 | 8083 | 153 | 169 | 946 |
| R Dravid | India | 343 | 10765 | 153 | 42 | 941 |
| Saeed Anwar | Pakistan | 247 | 8824 | 194 | 97 | 938 |
| HH Gibbs | South Africa | 252 | 8094 | 175 | 128 | 930 |
| KC Sangakkara | Sri Lanka | 294 | 9042 | 138 | 43 | 893 |
| JH Kallis | South Africa | 314 | 11227 | 139 | 130 | 880 |
| Yuvraj Singh | India | 280 | 8051 | 139 | 144 | 827 |
| SP Fleming | New Zealand | 281 | 8037 | 134 | 63 | 823 |
| DPMD Jayawardene | Sri Lanka | 344 | 9381 | 128 | 55 | 803 |
| DL Haynes | West Indies | 238 | 8648 | 152 | 53 | 768 |
| MS Atapattu | Sri Lanka | 274 | 8529 | 132 | 15 | 734 |
| S Chanderpaul | West Indies | 265 | 8765 | 150 | 85 | 722 |
| GC Smith | South Africa | 172 | 6280 | 141 | 38 | 722 |
| NJ Astle | New Zealand | 224 | 7090 | 145 | 86 | 720 |
| PA de Silva | Sri Lanka | 308 | 9284 | 145 | 102 | 712 |
| G Kirsten | South Africa | 185 | 6798 | 188 | 20 | 659 |
| ME Waugh | Australia | 244 | 8500 | 173 | 57 | 651 |
| ML Hayden | Australia | 161 | 6133 | 181 | 87 | 636 |
| M Azharuddin | India | 335 | 9378 | 153 | 77 | 622 |
| Shahid Afridi | Pakistan | 324 | 6695 | 124 | 289 | 615 |
| IVA Richards | West Indies | 187 | 6721 | 189 | 126 | 600 |
| TM Dilshan | Sri Lanka | 206 | 5445 | 160 | 35 | 558 |
